Intented Use:
Compass CLEAR PATH ™ Malaria Pan/P.f Antigen Rapid Test is a lateral flow immunochromatographic assay for the qualitative differential detection of pLDH (Plasmodium Lactate Dehydrogenase) specific Plasmodium Species (P. vivax / P. malariae / P. ovale) and HRP-2 (Histidine Rich Protein-2) specific P. falciparum in human whole blood specimens for professional use.
Intented Use:
Malaria Pan/P.f Antigen Rapid Test is a lateral flow chromatographic immunoassay. The strip test contains a pre-coated membrane strip, which consist a colored conjugate pad containing anti-PLDH antibody conjugated with colloidal gold (PLDH-gold conjugates) and anti-pHRP-II antibody conjugated with colloidal gold (pHRP-II-gold conjugates), and a nitrocellulose membrane strip containing two test bands “Pan” & “Pf” and a control band “C”. The “Pan” band is pre-coated with monoclonal antibody specific to anti-PLDH for the detection of PAN infection, the Pf band is pre-coated with monoclonal anti-pHRP-II antibodies for the detection of Pf infection, and the C band is coated with goat anti-rabbit IgG. During the assay, an adequate volume of the blood specimen is dispensed into the sample well (S) of the test cassette, and an assay buffer is added to the buffer well (B). The buffer contains a detergent that lyses the red blood cells and releases various antigens, which migrate by capillary action across the strip held in the cassette.
PLDH if present in the specimen will bind to the PLDH-gold conjugates. The immunocomplex is then captured on the membrane by the precoated anti-PLDH antibody, forming a burgundy colored PAN band, indicating a PAN positive test result. Alternatively, pHRP-II if present in the specimen will bind to the pHRP-II-gold conjugates. The immunocomplex is then captured on the membrane by the pre-coated antipHRP- II antibodies, forming a colored P.f band, indicating a P.f positive test result. Absence of any test bands suggests a negative result. The device indicating control line “C” indicating proper functioning of test device and proper procedure has been followed.
Available in packs of: 1Test, 5Test, 10Test, 20Test, 25Test, 30Test, 50Test, 100Test